CHLOROTHIAZIDE (klor oh THYE a zide) is a diuretic. It increases the amount of urine passed, which causes the body to lose salt and water. This medicine is used to treat high blood pressure. It is also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
immune system problems, like lupus
small amount of urine or difficulty passing urine
an unusual or allergic reaction to chlorothiazide, sulfa drugs, or other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your doses at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not stop taking your medicine unless your doctor tells you to.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
barbiturates, like phenobarbital
medicines for diabetes
medicines for high blood pressure
medicines for high cholesterol, like cholestyramine or colestipol
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
prescription pain medicines
skeletal muscle relaxants like tubocurarine
steroid medicines like prednisone or cortisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.
You may need to be on a special diet while taking this medicine. Ask your doctor.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heartbeat
feeling faint or lightheaded, falls
muscle pain or cramps
numbness or tingling in hands, feet, or lips
pain or trouble when passing urine
redness, blistering, peeling or loosening of the skin, including inside the mouth
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not stop taking your medicine unless your doctor tells you to.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Keep container closed tightly. Throw away any unused medicine after the expiration date.
kidney or liver disease
systemic lupus erythematosus
an unusual or allergic reaction to chlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
This medicine may be injected or infused into a vein. It is usually given by a health-care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
This does not apply.
barbiturates like phenobarbital
NSAIDs like ibuprofen
some cholesterol-lowering medications like cholestyramine or colestipol
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
This drug is given in a hospital or clinic and will not be stored at home.