Dinoprostone, Prostaglandin E2Dinoprostone, Prostaglandin E2

Dinoprostone Vaginal gel

What is this medicine?

DINOPROSTONE, PROSTAGLANDIN E2 (dye noe PROST one; pros tuh GLAN din) is used to help dilate the cervix in pregnant women who are at or near term. This will help to induce labor.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:

  • active genital herpes infection

  • placenta previa

  • previous pregnancy with difficult labor, traumatic delivery or cesarean section

  • previous surgery to the uterus

  • vaginal bleeding, inflammation or infection

  • 6 or more previous pregnancies

  • an unusual or allergic reaction to dinoprostone, prostaglandins, other medicines, foods, dyes, or preservatives

  • breast-feeding

How should I use this medicine?

This medicine is inserted into the vagina by a health-care professional in a hospital or clinic setting. Remain lying down for 15 to 30 minutes after it is inserted.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

  • oxytocin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

You will be closely monitored while you receive this medicine.

This medicine can affect other muscles outside of the uterus and cause side effects. Most of these effects will go away quickly.

Contact your doctor or health care professional immediately if you get an unpleasant vaginal discharge, continued fever, chills and shivering, or increase in vaginal bleeding several days after treatment.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • continuous or excessive vaginal bleeding

  • excessive abdominal or cramping pains

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • diarrhea

  • fever

  • headache

  • nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This does not apply. You will not be given this medicine to store at home.


Dinoprostone Vaginal insert

What is this medicine?

DINOPROSTONE, PROSTAGLANDIN E2 (dye noe PROST one, pros tuh GLAN din) is used to help dilate the cervix in pregnant women who are at or near term. This will help to induce labor.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:

  • active genital herpes infection

  • placenta previa

  • previous pregnancy with difficult labor, traumatic delivery or cesarean section

  • previous surgery to the uterus

  • vaginal bleeding, inflammation or infection

  • 6 or more previous pregnancies

  • an unusual or allergic reaction to dinoprostone, prostaglandins, other medicines, foods, dyes, or preservatives

  • breast-feeding

How should I use this medicine?

This medicine is inserted into the vagina by a health-care professional in a hospital or clinic setting. Remain lying down for 2 hours after it is inserted. After the 2 hours, you may walk around. Your doctor will remove the insert after it has been in place for 12 hours or after active labor beings.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

  • oxytocin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

You will be closely monitored while you receive this medicine.

This medicine can affect other muscles outside of the uterus and cause side effects. Most of these effects will go away quickly.

Contact your doctor or health care professional immediately if you get an unpleasant vaginal discharge, continued fever, chills and shivering, or increase in vaginal bleeding several days after treatment.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • continuous or excessive vaginal bleeding

  • excessive abdominal or cramping pains

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • fever

  • headache

  • nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This does not apply. You will not be given this medicine to store at home.


Dinoprostone Vaginal suppository

What is this medicine?

DINOPROSTONE, PROSTAGLANDIN E2 (dye noe PROST one pros tuh GLAN din) stimulates contractions to empty the uterus. Sometimes it is used after a miscarriage. It can be used when necessary to induce abortion between the 12th and 20th week of pregnancy. This medicine may also be used to treat a condition called benign hydatidiform mole.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:

  • heart disease

  • kidney disease

  • liver disease

  • lung or breathing disease, like asthma

  • vaginal inflammation or infection

  • an unusual or allergic reaction to dinoprostone, prostaglandins, other medicines, foods, dyes, or preservatives

  • breast-feeding

How should I use this medicine?

This medicine is inserted into the vagina by a health-care professional in a hospital or clinic setting. Remain lying down for 10 minutes after it is inserted.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

  • oxytocin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

You will be closely monitored while you receive this medicine.

This medicine can affect other muscles outside of the uterus and cause side effects. Most of these effects will go away quickly.

Contact your doctor or health care professional immediately if you get an unpleasant vaginal discharge, continued fever, chills and shivering, or increase in vaginal bleeding several days after treatment.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • chest pain or palpitations

  • continuous or excessive vaginal bleeding

  • dizziness or fainting

  • fever

  • foul smelling vaginal discharge

  • abdominal pain, or severe cramping pains

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • chills or shivering

  • hot flashes

  • headache

  • nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This does not apply. You will not be given this medicine to store at home.


 
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