Erythema nodosum is characterized by tender, red bumps, usually found symmetrically on the shins. Up to 55 percent of cases have no clear identifiable cause. Sometimes, erythema nodosum is not a separate disease, but, rather, a sign of some other infection, disease, or of a sensitivity to a drug.
Sarcoidosis (inflammation of the lymph nodes and other organs)
Coccidioidomycosis (infection of the upper respiratory tract and lungs)
Histoplasmosis (an infectious pulmonary disease)
Psittacosis (a flu-like disease)
Antibiotics containing sulfa or penicillin
The following are the most common symptoms of erythema nodosum. However, each individual may experience symptoms differently. Symptoms may include:
Raised bruises on the shins
Enlarged lymph nodes in the chest
Young adults are particularly susceptible to erythema nodosum. The symptoms of erythema nodosum may resemble other skin conditions. Always consult your doctor for a diagnosis.
A biopsy (removal of tissue for examination under a microscope) of a bump can usually confirm the diagnosis along with comprehensive lab work. However, the exact cause cannot always be identified. Drug-induced erythema nodosum can usually be diagnosed by elimination of the drug causing the reaction. A throat swab may be done to check for strep infection.
Specific treatment for erythema nodosum will be determined by your doctor based on:
Your age, overall health, and medical history
Extent of the condition
Your tolerance for specific medications, procedures, or therapies
Expectations for the course of the condition
Your opinion or preference
Treatment may include:
Antibiotics to treat an underlying bacterial infection
Treatment of other underlying cause
Bed rest (to relieve pain)
Nonsteroidal anti-inflammatory drugs
Although erythema nodosum is uncomfortable, it is usually not a serious condition. Symptoms are usually gone within six weeks; however, they may recur.