ALTEPLASE (AL te plase) can dissolve blood clots that form in the heart, blood vessels, or lungs after a heart attack. This medicine is also given to improve recovery and decrease the chance of disability in patients having symptoms of a stroke.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
bleeding problems or problems with blood clotting
blood vessel disease or damaged blood vessels
head injury or tumor
high blood pressure
recent biopsy or surgery
an unusual or allergic reaction to alteplase, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
This does not apply.
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
antiinflammatory drugs, NSAIDs like ibuprofen
aspirin and aspirin-like medicines
blood thinners, like warfarin, heparin or enoxaparin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Your condition will be monitored carefully while you are receiving this medicine. Follow the advice of your doctor or health care professional exactly. You may need bed rest to minimize the risk of bleeding.
This medicine can make you bleed more easily. This effect can last for several days. Take special care brushing or flossing your teeth.
Do not take aspirin, ibuprofen, or other nonprescription pain relievers during or for several days after alteplase treatment unless otherwise instructed by your doctor or health care professional.
You may feel dizzy or lightheaded. To avoid the risk of dizzy or fainting spells, sit or stand up slowly, especially if you are an older patient.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blood in the urine, stools, or vomit
chest pain or tightness
shortness of breath
slow or fast heart rate
unusual bleeding, bruising, or purple spots on the skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This does not apply. You will not be given this medicine to store at home.