METFORMIN; ROSIGLITAZONE (met FOR min; roe si GLI ta zone) is a combination medicine used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
become easily dehydrated
frequently drink alcohol-containing beverages
history of diabetic ketoacidosis
polycystic ovary syndrome
serious infection or injury
swelling of the arms, legs, or feet; water retention
undergoing surgery or certain x-ray procedures with injectable contrast agents
an unusual or allergic reaction to metformin; rosiglitazone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with meals. Take your medicine at the same time each day. Do not take more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
certain contrast medicines given before X-rays, CT scans, MRI, or other procedures
This medicine may also interact with the following medications:
female hormones, like estrogens or progestins and birth control pills
medicines for blood pressure, heart disease, irregular heart beat
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
steroid medicines like prednisone or cortisone
stimulant medicines for attention disorders, weight loss, or to stay awake
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress.
Your health care professional will have to check blood tests regularly to assess the effect of this medication on your liver.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them. If you have low blood sugar, eat or drink something that has sugar. Make sure others know to get medical help quickly if you have serious symptoms of low blood sugar, like if you become unconscious or have a seizure.
If you need surgery or if you will need a procedure with contrast drugs, tell your doctor or health care professional that you are taking this medicine.
Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
bone or joint pain
chest pain or tightness
muscle aches or pains
nausea, vomiting, unusual stomach upset or pain
pain that radiates to the jaw or down the arm
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
sudden weight gain
swelling of the ankles, feet, hands
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
metallic taste in mouth
stuffy or runny nose
stomach gas, upset
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.