Dextromethorphan; Quinidine

Dextromethorphan Hydrobromide, Quinidine Sulfate Oral capsule

What is this medicine?

DEXTROMETHORPHAN; QUINIDINE (dex troe meth OR fan; KWIN i deen) is a combination of two medicines used to treat pseudobulbar affect (PBA), a condition that causes uncontrollable, sudden, and frequent episodes of laughing and/or crying.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • history of low blood counts caused by a medicine

  • history of irregular heartbeat

  • kidney disease

  • liver disease

  • low levels of magnesium or potassium in the blood

  • myasthenia gravis

  • an unusual or allergic reaction to dextromethorphan, quinidine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • arsenic trioxide

  • certain antipsychotics like chlorpromazine, clozapine, haloperidol, mesoridazine, olanzapine, perphenazine, pimozide, risperidone, sertindole, thioridazine, ziprasidone

  • certain medicines for irregular heart beat like amiodarone, bepridil, dofetilide, encainide, flecainide, propafenone, quinidine

  • certain medicines used to treat infections like chloroquine, clarithromycin, erythromycin, pentamidine, posaconazole

  • certain medicines used for nausea like dolasetron, droperidol, ondansetron, palonosetron

  • cisapride

  • cyclobenzaprine

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • mefloquine

  • methadone

  • quinine

  • ranolazine

This medicine may also interact with the following medications:

  • alcohol

  • aprepitant

  • certain antiviral medicines for HIV or AIDS

  • certain medicines for depression or anxiety

  • certain medicines for fungal infections like fluconazole, ketoconazole, and itraconazole

  • codeine

  • digoxin

  • diltiazem

  • grapefruit juice

  • hydrocodone

  • memantine

  • tacrolimus

  • telavancin

  • telithromycin

  • tetrabenazine

  • vardenafil

  • verapamil

  • vorinostat

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.

You may get dizzy. Contact your doctor right away if you feel faint or have fainting spells while taking this medicine. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks; they can make you more dizzy.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • changes in vision

  • chills

  • confusion

  • decreased hearing

  • fast or irregular heartbeat

  • feeling faint or lightheaded, falls

  • fever

  • muscle pain

  • ringing of the ears

  • sensitivity to light

  • unusual bleeding or bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • cough

  • diarrhea

  • dizziness

  • drowsiness

  • headache

  • nausea, vomiting

  • stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.


 

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