MEPIVACAINE (Carbocaine®, Polocaine®) is a drug that is injected before and during various surgical or dental procedures or labor and delivery. Mepivacaine causes loss of feeling in the skin and surrounding tissues. Generic mepivacaine injections are available.
They need to know if you have any of the following conditions:
blood clotting problems
heart or blood vessel disease
an unusual or allergic reaction to mepivacaine, local anesthetics, parabens, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Mepivacaine is injected into a specific area to make it numb before a surgery or other procedure. Depending on the type of procedure it may be given into the area around your spine, into your gums, or into other areas so you will not feel pain during the procedure. Only a specially trained health-care professional will give mepivacaine in a hospital or clinic.
This does not apply.
Mepivacaine has the potential to interact with many medications. The list below contains some of the drugs that can interact.
Do not take mepivacaine with any of the following medications:
certain antibiotics: clarithromycin, erythromycin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin, telithromycin, or troleandomycin
certain drugs to treat depression called monoamine oxidase inhibitors (MAOIs) such as isocarboxazid and phenelzine
certain medicines for your heart (examples- flecainide, propafenone, amiodarone, disopyramide, dofetilide, ibutilide, procainamide, quinidine, sotalol)
some medicines for treating depression or other mental problems (examples- amoxapine, chlorpromazine, clozapine, fluphenazine, halofantrine, haloperidol, maprotiline, mesoridazine, perphenazine, prochlorperazine, risperidone, sertindole, thioridazine, tricyclic antidepressants, trifluoperazine)
Mepivacaine may also interact with the following medications:
ergotamine or dihydroergotamine (DHE)
Tell your prescriber or health care professional about all other medicines that you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Let your prescriber or health care professional know if the feeling of numbness that mepivacaine causes does not wear off within a few hours, or if you find it hard to open your mouth.
After an injection of mepivacaine the area will be numb for some time and you will not be aware of pain. Try to avoid injury to the area. If the injection was given in your mouth, do not chew gum or food until the numbness wears off. You could bite your tongue or the inside of your cheeks.
Side effects that you should report to your prescriber or health care professional as soon as possible:
difficulty breathing, shortness of breath
dizziness, drowsiness, lightheadedness
skin rash, itching (hives)
slow, irregular heartbeat (palpitations)
swelling of the face or mouth
If they are going to occur, these side effects may become apparent before you leave the hospital, clinic or dental office. Call your health care provider as soon as you can if you get any of the above reactions later.
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
numbness or tingling of the face or mouth
pain at the injection site
You will only receive mepivacaine in a hospital or clinic setting prior to surgery or other procedures. You will not need to take this medicine at home.