Tretinoin, ATRATretinoin, ATRA

Aloe Vera/Aloe Barbadensis Derivatives, Beeswax, Benzyl Alcohol, Bisabolol, Butylene Glycol, Carbomers, cetearyl alcohol, Dimethicone, Distilled Water, Glycerin, Green Tea, Hydroxyethyl Cellulose, Imidazolidinyl urea , Laureth, Methylparaben, Polyethylene Glycol, Polysorbate 60, PPG-2, Propylparaben, Squalane, tetrasodium EDTA, Triethanolamine Topical solution, Citric Acid, Co-Enzyme Q-10 , Cocamidopropyl Betaine, Cocoyl monoethanolamine, Disodium cocoamphodiacetate, Distilled Water, Green Tea, Methylparaben, Panthenol, Phenoxyethanol, Polyethylene Glycol, polyquatemium, Propylparaben, Sodium Chloride, Sodium laureth sulfate, tetrasodium EDTA Topical suspension, cleanser, Tretinoin Topical gel

What is this medicine?

TRETINOIN (TRET i noe in) is a naturally occurring form of vitamin A. It is used on the skin to treat mild to moderate acne.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eczema

  • excessive sensitivity to the sun

  • sunburn

  • an unusual or allergic reaction to fish (Atralin only), tretinoin, vitamin A, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Wait 20 to 30 minutes for your skin to dry before use in order to minimize the possibility of skin irritation. Apply enough medicine to cover the affected area and rub in gently. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. Do not use more often than your doctor or health care professional has recommended. Using too much of this medicine may irritate or increase the irritation of your skin, and will not give faster or better results.

Talk to your pediatrician or health care professional regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • medicines or other preparations that may dry your skin such as benzoyl peroxide or salicylic acid

  • medicines that increase your sensitivity to sunlight such as tetracycline or sulfa drugs

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your acne may get worse initially and should then start to improve. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 2 or 3 times a day, unless directed by your doctor or health care professional. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect such as products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid cold weather and wind as much as possible, and use clothing to protect you from the weather. Skin treated with this medicine may dry out or get wind burned more easily.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • darkening or lightening of the treated areas

  • severe burning, itching, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • increased sensitivity to the sun

  • itching

  • mild stinging

  • red, inflamed, and irritated skin, the skin may peel after a few days

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Keep away from heat and flame. Protect from light. Throw away any unused medicine after the expiration date.


Tretinoin Oral capsule

What is this medicine?

TRETINOIN (TRET i noe in) is a medicine belonging to a class called the retinoids. It is similar to vitamin A. It is used to treat certain leukemias, such as acute promyelocytic leukemia (APL).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • high cholesterol

  • liver disease

  • an unusual or allergic reaction to tretinoin, vitamin A, parabens, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • other retinoids

  • vitamin A supplements

This medicine may also interact with the following medications:

  • aminocaproic acid

  • aprotinin

  • cimetidine

  • cyclosporine

  • diltiazem

  • erythromycin

  • medicines for fungal infections like ketoconazole, itraconazole, and voriconazole

  • medicines that increase your sensitivity to sunlight such as tetracyclines or sulfa drugs

  • methotrexate

  • orlistat

  • phenobarbital

  • rifampin

  • steroid medicines like prednisone or cortisone

  • tranexamic acid

  • verapamil

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You will need to have regular blood checks.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. You should have a pregnancy test within 1 week before starting this medicine. Use 2 kinds of birth control and take monthly pregnancy tests while you are taking this medicine and for 1 month after stopping this medicine. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.

  • signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine

  • signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine

  • signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness

  • breathing problems

  • changes in blood pressure

  • changes in emotions or moods

  • changes in hearing

  • changes in vision

  • chest pain

  • confusion

  • depressed mood

  • hallucination, loss of contact with reality

  • mouth sores

  • nausea, vomiting

  • pain, tingling, numbness in the hands or feet

  • problems with balance, talking, walking

  • seizures

  • stomach pain

  • swelling of the ankles, feet, hands

  • trouble passing urine or change in the amount of urine

  • water or weight gain

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • bone pain

  • changes in skin color

  • dry skin

  • hair loss

  • headache

  • increased sweating

  • loss of appetite

  • stomach upset

  • trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at 15 to 30 degrees C (59 to 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.


Tretinoin Topical cream

What is this medicine?

TRETINOIN (TRET i noe in) is a naturally occurring form of vitamin A. It is used on the skin to treat mild to moderate acne.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eczema

  • excessive sensitivity to the sun

  • sunburn

  • an unusual or allergic reaction to tretinoin, vitamin A, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Wait 20 to 30 minutes for your skin to dry before use in order to minimize the possibility of skin irritation. Apply enough medicine to cover the affected area and rub in gently. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. Do not use more often than your doctor or health care professional has recommended. Using too much of this medicine may irritate or increase the irritation of your skin, and will not give faster or better results.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • medicines or other preparations that may dry your skin such as benzoyl peroxide or salicylic acid

  • medicines that increase your sensitivity to sunlight such as tetracycline or sulfa drugs

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your acne may get worse initially and should then start to improve. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 2 or 3 times a day, unless directed by your doctor or health care professional. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect such as products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid cold weather and wind as much as possible, and use clothing to protect you from the weather. Skin treated with this medicine may dry out or get wind burned more easily.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • darkening or lightening of the treated areas

  • severe burning, itching, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • increased sensitivity to the sun

  • itching

  • mild stinging

  • red, inflamed, and irritated skin, the skin may peel after a few days

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store below 27 degrees C (80 degrees F). Do not freeze. Protect from light. Throw away any unused medicine after the expiration date.


Tretinoin Topical cream [Cosmetic Use]

What is this medicine?

TRETINOIN (TRET i noe in) is a naturally occurring form of vitamin A. It is used on the skin to treat the effects of aging on the face, such as fine lines, wrinkles, or age spots.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eczema

  • excessive sensitivity to the sun

  • sunburn

  • an unusual or allergic reaction to tretinoin, vitamin A, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Wait 20 to 30 minutes for your skin to dry before use in order to minimize the possibility of skin irritation. Apply enough medicine to cover the affected area and rub in gently. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. Do not use more often than your doctor or health care professional has recommended. Using too much of this medicine may irritate your skin, and will not give faster or better results.

Talk to your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • medicines or other preparations that may dry your skin such as benzoyl peroxide or salicylic acid

  • medicines that increase your sensitivity to sunlight such as tetracycline or sulfa drugs

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

You may not notice any improvements in your facial lines right away. It may take up to 4 months to see any effects. This medicine does not completely remove wrinkles or repair sun damaged skin.

Do not wash your face more than 2 or 3 times a day, unless directed by your doctor or health care professional. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect such as products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid cold weather and wind as much as possible, and use clothing to protect you from the weather. Skin treated with this medicine may dry out or get wind burned more easily.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • darkening or lightening of the treated areas

  • severe burning, itching, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • increased sensitivity to the sun

  • itching

  • mild stinging

  • red, inflamed, and irritated skin, the skin may peel after a few days

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Protect from light. Throw away any unused medicine after the expiration date.


Tretinoin Topical gel

What is this medicine?

TRETINOIN (TRET i noe in) is a naturally occurring form of vitamin A. It is used on the skin to treat mild to moderate acne.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eczema

  • excessive sensitivity to the sun

  • sunburn

  • an unusual or allergic reaction to fish (Atralin only), tretinoin, vitamin A, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Wait 20 to 30 minutes for your skin to dry before use in order to minimize the possibility of skin irritation. Apply enough medicine to cover the affected area and rub in gently. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. Do not use more often than your doctor or health care professional has recommended. Using too much of this medicine may irritate or increase the irritation of your skin, and will not give faster or better results.

Talk to your pediatrician or health care professional regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • medicines or other preparations that may dry your skin such as benzoyl peroxide or salicylic acid

  • medicines that increase your sensitivity to sunlight such as tetracycline or sulfa drugs

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your acne may get worse initially and should then start to improve. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 2 or 3 times a day, unless directed by your doctor or health care professional. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect such as products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid cold weather and wind as much as possible, and use clothing to protect you from the weather. Skin treated with this medicine may dry out or get wind burned more easily.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • darkening or lightening of the treated areas

  • severe burning, itching, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • increased sensitivity to the sun

  • itching

  • mild stinging

  • red, inflamed, and irritated skin, the skin may peel after a few days

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Keep away from heat and flame. Protect from light. Throw away any unused medicine after the expiration date.


Tretinoin Topical solution

What is this medicine?

TRETINOIN (TRET i noe in) is a naturally occurring form of vitamin A. It is used on the skin to treat mild to moderate acne.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • eczema

  • excessive sensitivity to the sun

  • sunburn

  • an unusual or allergic reaction to tretinoin, vitamin A, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for use on the skin. Do not take by mouth. Follow the directions on the prescription label. Gently wash your face with a mild, non-medicated soap before use. Pat the skin dry. Wait 20 to 30 minutes for your skin to dry before applying in order to minimize the possibility of skin irritation. Wash hands before and after use. The liquid may be applied to the skin where the acne lesions appear, spreading the medicine over the entire affected area using your fingertip, a gauze pad, or cotton swab. To avoid dripping the liquid onto areas that do not need treatment, do not soak the cotton or gauze. Avoid applying this medicine to your eyes, ears, nostrils, angles of the nose, and mouth. Do not use more often than your doctor or health care professional has recommended. Using too much of this medicine may irritate or increase the irritation of your skin, and will not give faster or better results.

Talk to your pediatrician or health care professional regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • medicines or other preparations that may dry your skin such as benzoyl peroxide or salicylic acid

  • medicines that increase your sensitivity to sunlight such as tetracycline or sulfa drugs

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your acne may get worse initially and should then start to improve. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 2 or 3 times a day, unless directed by your doctor or health care professional. Do not use the following products on the same areas that you are treating with this medicine, unless otherwise directed by your doctor or health care professional: other topical agents with a strong skin drying effect such as products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid cold weather and wind as much as possible, and use clothing to protect you from the weather. Skin treated with this medicine may dry out or get wind burned more easily.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • darkening or lightening of the treated areas

  • severe burning, itching, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • increased sensitivity to the sun

  • itching

  • mild stinging

  • red, inflamed, and irritated skin, the skin may peel after a few days

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F). Do not freeze. Protect from light. Throw away any unused medicine after the expiration date.


 
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