Premature rupture of membranes (PROM) is a rupture (breaking open) of the membranes (amniotic sac) before labor begins. If PROM occurs before 37 weeks of pregnancy, it is called preterm premature rupture of membranes (PPROM).
PROM occurs in about 8% to 10% of all pregnancies. PPROM (before 37 weeks) accounts for one-fourth to one-third of all preterm births.
Rupture of the membranes near the end of pregnancy (term) may be caused by a natural weakening of the membranes or from the force of contractions. Before term, PPROM is often due to an infection in the uterus. Other factors that may be linked to PROM include the following:
Low socioeconomic conditions (as women in lower socioeconomic conditions are less likely to receive proper prenatal care)
Sexually transmitted diseases, such as chlamydia and gonorrhea
Previous preterm birth
Cigarette smoking during pregnancy
PROM is a complicating factor in as many as one-third of premature births. A significant risk of PPROM is that most babies are born within a week of the membrane rupture. Another major risk of PROM is development of a serious infection of the placental tissues called chorioamnionitis. This can be very dangerous for mother and baby. Other complications that may occur with PROM include placental abruption (early detachment of the placenta from the uterus), compression of the umbilical cord, cesarean birth, and postpartum (after delivery) infection.
The following are the most common symptoms of PROM:
Leaking or a gush of watery fluid from the vagina
Constant wetness in underwear
If you notice any symptoms of PROM, be sure to call your health care provider as soon as possible. The symptoms of PROM may look like other conditions medical problems. Always see your health care provider for a diagnosis.
In addition to a complete medical history and physical exam, PROM may be diagnosed in several ways, including the following:
An exam of the cervix (may show fluid leaking from the cervical opening)
Testing of the pH (acid or alkaline) of the fluid
Looking at the dried fluid under a microscope (may show a characteristic fern-like pattern)
Ultrasound. A diagnostic imaging technique that uses high-frequency sound waves and a computer to create images of blood vessels, tissues, and organs. Ultrasounds are used to view internal organs as they function, and to assess how much fluid is around the baby.
Your health care provider will figure out the best treatment for you based on:
Your overall health and medical history
How well you can handle specific medications, procedures, or therapies
How long the condition is expected to last
Your opinion or preference
Treatment for preterm premature rupture of membranes may include:
Expectant management (in very few cases of PPROM, the membranes may seal over and the fluid may stop leaking without treatment, although this is uncommon unless PROM was from a procedure, such as amniocentesis, early in gestation)
Monitoring for signs of infection, such as fever, pain, increased fetal heart rate, and/or lab tests.
Giving the mother medications called corticosteroids that may help mature the lungs of the fetus (lung immaturity is a major problem of premature babies). However, corticosteroids may mask an infection in the uterus.
Antibiotics (to prevent or treat infections) and to prolong the time to delivery
Tocolytics. Medications used to stop preterm labor.
Women with PPROM usually are induced to deliver at 34 weeks if stable. If there are signs of abruption, chorioamnionitis, or fetal compromise, then early delivery would be necessary.)
Unfortunately, there is no way to actively prevent PROM. However, this condition does have a strong link with cigarette smoking and mothers should stop smoking as soon as possible.