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PENTETATE ZINC TRISODIUM (Zn-DTPA) is used to remove certain radioactive materials from the body after a radiation exposure. Zn-DTPA will speed up the removal of plutonium, americium and curium from the body, but it may not prevent all the problems associated with radiation exposure. Generic inhalations are not available.
They need to know if you have any of these conditions:
an unusual reaction to Zn-DTPA, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Zn-DTPA inhalation is for use in a nebulizer. A nebulizer allows the Zn-DTPA solution to be delivered as an aerosol for inhalation through the mouth and into the lungs. Follow the directions for correct use of the nebulizer. After treatment, avoid swallowing any materials you cough up. Follow the directions on the prescription label. Take your doses at regular intervals.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
Follow your prescriber's advice regarding the need for continued doses. If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
no drug interactions have been reported
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Zn-DTPA should be given only under the supervision of a physician after assessing your medical condition. It is only effective to treat contamination with radioactive plutonium, americium and curium. This drug does not help eliminate other forms of radiation from the body.
How long you will need treatment depends on the amount of contamination you were exposed to. You will have regular check-ups to determine the level of radiation in your body. The amount of radiation in your body will determine how long you have to take Zn-DTPA.
Drink plenty of fluids and urinate frequently to help radiation removal from the body.
You will be given instructions to reduce the chance of exposing others to radiation. For example, some radiation gets into the urine and stool. A toilet should be used instead of a urinal, and it should be flushed several times after each use. Spilled urine or stool should be cleaned up completely. Wash your hands thoroughly and often. If body fluids soil clothing, wash the clothes separately. Dispose of any expectorant (fluid you cough up) carefully.
Side effects that you should report to your prescriber or health care professional as soon as possible:
difficulty breathing, shortness of breath, wheezing
fast or uneven heart beat, palpitations or chest pain
skin rash or hives
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
nausea or vomiting
Keep out of the reach of children in a container that small children cannot open.
Store at controlled room temperature, preferably between 15—30 degrees C (59—86 degrees F). Do not freeze. Throw away any unused medicine after the expiration date
PENTETATE ZINC TRISODIUM (Zn-DTPA) is used to remove certain radioactive materials from the body after a radiation exposure. Zn-DTPA will speed up the removal of plutonium, americium and curium from the body, but it may not prevent all the problems associated with radiation exposure. Generic injections are not available.
Zn-DTPA injection is for slow infusion into a vein. A health care professional will give this medication to you.
Follow your prescriber's advice regarding the need for continued doses once you have received the first dose. Make sure you keep appointments for further doses.
Store at controlled room temperature, preferably between 15—30 degrees C (59—86 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Bayhealth is Southern Delaware’s healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women’s services.