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DEFERASIROX (de FER a sir ox) binds to iron in the blood. It helps to prevent and treat too much iron in the blood caused by blood transfusions.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
a blood disorder
low blood counts, like low white cell, platelet, or red cell counts
an unusual or allergic reaction to deferasirox, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth. Do not chew or take tablets whole. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before food. Do not take with food. Before taking, mix the dose in water, orange juice, or apple juice as directed. If your dose is less than 1 gram, use 3.5 ounces or about 1/2 glass of liquid. If your dose is 1 gram or more, use 7 ounces or about 1 full glass of liquid. Stir the medicine into the liquid until the tablets dissolve. Drink your dose right away after mixing. If there is any medicine left in the glass after you drink the mixture, add a little bit more liquid, swirl it around, and drink. Take your doses at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
antacids that have aluminum
iron supplements or vitamins that have iron
other iron binders like deferoxamine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor for regular check ups. You will need important blood work, vision tests, and hearing tests done while you are taking this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Avoid taking antacids containing aluminum at the same time as this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black or bloody stools or blood in vomit
changes in hearing
changes in vision
fever or chills, sore throat
general ill feeling or flu-like symptoms
loss of appetite, nausea
right upper belly pain
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
DEFERASIROX (de FER a sir ox) binds to iron in the blood. It helps to treat too much iron in the blood.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach. Take this medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
birth control pills
certain medicines for blood pressure, heart disease, irregular heart beat like conivaptan, dronedarone, eplerenone, felodipine, nisoldipine, quinidine, tolvaptan
certain medicines for cholesterol like cholestyramine, colesevelam, colestipol, lovastatin, simvastatin
certain medicines for depression, anxiety, or psychotic disturbances like buspirone, duloxetine, lurasidone, melatonin, midazolam, pimozide, quetiapine, ramelteon, tacrine, triazolam
certain medicines for erectile dysfunction like sildenafil, vardenafil
certain medicines for HIV like darunavir, indinavir, lopinavir; ritonavir, maraviroc, saquinavir, ritonavir, tipranavir
certain medicines for migraine headaches like dihydroergotamine, eletriptan, ergotamine
certain medicines for pain like alfentanil, fentanyl
certain medicines for seizures like phenobarbital, phenytoin
certain medicines that lower your chance of fighting infection like budesonide, cyclosporine, dasatinib, everolimus, fluticasone, paclitaxel, sirolimus, tacrolimus
theophylline and caffeine
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Bayhealth is Southern Delaware’s healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women’s services.