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TEMSIROLIMUS (TEM sir OH li mus) is a drug that alters immune system response in the body. It is used to treat renal cell cancer.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
immune system problems
infection (especially a virus infection such as chickenpox, cold sores, or herpes)
low blood counts, like low white cell, platelet, or red cell counts
lung or breathing disease, like asthma
take medicines that treat or prevent blood clots
an unusual or allergic reaction to temsirolimus, polysorbate 80, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Do not take this medicine with any of the following medications:
St. John's Wort
This medicine may also interact with the following medications:
medicines for heart or kidney problems like captopril, lisinopril
medicines for infection like clarithromycin, itraconazole, ketoconazole, rifabutin, rifampin, telithromycin
some medicines for HIV like atazanavir, indinavir, nelfinavir, ritonavir, saquinavir
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor for regular check-ups. you will need important blood work done while you are taking this medicine.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Women who are able to have children should use effective birth control before, during, and for 12 weeks after stopping this medicine. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems, cough
fever or chills, sore throat
hallucination, loss of contact with reality
increased hunger or thirst
pain, swelling, warmth in the leg
redness, blistering, peeling or loosening of the skin, including inside the mouth
swelling of the legs or ankles
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
loss of appetite
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This drug is given in a hospital or clinic and will not be stored at home.
Bayhealth is Southern Delaware’s healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women’s services.