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MIFEPRISTONE (mi FE pri stone) is a hormone-like drug. This medicine is available in products that are used for different purposes.
Mifeprex is used in combination with other medicines to end an early pregnancy (usually during the first 10 weeks). This medicine is only available in a doctor's office, health clinic, or hospital.
Korlym is used to treat Cushing's disease.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
For use of Mifeprex:
adrenal gland problems
cannot easily get emergency medical help in the 2 weeks after you take this medicine
cannot return for follow up appointments in 1 to 2 weeks after you take this medicine
have an intrauterine device (IUD)
it has been more than 70 days (10 weeks) since your last menstrual period began
take medicines that treat or prevent blood clots like enoxaparin, warfarin
take steroid medicines like prednisone or cortisone
tubal or ectopic pregnancy
an unusual or allergic reaction to mifepristone, misoprostol, prostaglandins, or other medicines, foods, dyes, or preservatives
For use of Korlym:
diabetes not related to Cushing's disease
take medicines that treat or prevent blood clots
unexplained vaginal bleeding
uterine cancer or cancer of the uterine lining
an unusual or allergic reaction to mifepristone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Mifeprex: Take this medicine by mouth with a glass of water. It will only be given to you by a health care professional while you are in the hospital, medical office, or clinic. Before you take this medicine, read the information your doctor or health care provider gives you. Talk to your doctor about any questions you have.
Korlym: Take this medicine by mouth with a glass of water. Take at about the same time each day. Swallow the tablets whole. Do not cut, crush, or chew this medicine. Take it with food.Do not take with grapefruit juice. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
Mifeprex: This does not apply.
Korlym: If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines that treat or prevent blood clots like enoxaparin, warfarin
steroid medicines like prednisone or cortisone
This medicine may also interact with the following medications:
certain medicines for seizures like carbamazepine, phenytoin, phenobarbital
certain medicines used in surgery for anesthesia
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
St. John's wort or other herbal products
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
For your safety, you must visit your doctor as directed after taking this medicine. Report any unusual effects to your doctor. This medicine can cause birth defects. You will need surgery if this medicine fails to cause a full abortion.
After you take this medicine, some vaginal bleeding is normal. Heavy bleeding may be a sign that something is wrong. If you soak through 2 thick full-size sanitary pads each hour for 2 hours, get medical help right away. Call your doctor if you have a fever, stomach pain or tenderness, nausea, vomiting, diarrhea, or feel weak. This may be a sign that something is wrong. You may have a serious infection or complication and need medical help.
Keep the MedGuide for this medicine. If you need emergency medical care, show your healthcare provider the MedGuide. Tell the health care provider that you have taken this medicine.
Visit your doctor or health care professional for regular checks on your progress. You will need blood work done while you are taking this medicine.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Women will need a pregnancy test prior to starting this medicine. Do not become pregnant while taking this medicine or for 1 month after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
Women must use effective birth control with this medicine. Use a non-hormonal form of birth control while taking this medicine and for 1 month after stopping it. Talk to your health care professional about how to prevent pregnancy. Tell your doctor right away if you think you may be pregnant.
Do not breast-feed an infant while taking this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heartbeat
feeling faint, lightheaded
fever or chills
unusually weak or tired
vaginal discharge with bad smell
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loss of appetite
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Mifeprex: This drug is given in a hospital or clinic and will not be stored at home.
Korlym: Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Bayhealth is Southern Delaware’s healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women’s services.