640 South State StreetDover, Delaware 19901
21 West Clarke AvenueMilford, Delaware 19963
401 North Carter RoadSmyrna, DE 19977
640 S. State StreetDover DE 1990121 West Clarke AvenueMilford DE 19963
301 Jefferson AveMilford, DE 19963
1275 S. State StreetDover, Delaware 19901
Human leukocyte antigen (HLA) typing
This test looks at the human leukocyte antigens (HLA) in your blood. This test is used if you need an organ or stem-cell transplant, to find an organ or stem cells that are as close to yours as possible. An improper match if you need a stem-cell transplant could cause the stem cells to harm you. A mismatched organ transplant can cause the organ to fail and be rejected.
HLAs are proteins found on the surface of most of the cells in your body. They signal to your immune system which cells are parts of your body and which cells are potentially harmful organisms. They play an important role in protecting you from infections, but they also make organ transplants more difficult.
HLAs are also involved in autoimmune diseases. These are diseases in which the body attacks its own tissues. The HLA test can be used to identify these diseases.
You may have this test if you need an organ or stem-cell transplant. A heart, lung, or kidney transplant may be needed if your own organ is no longer able to work as it should. Testing helps make sure you have the best possible match between your HLA antigens and those on the organ you receive. You may also need this test if your healthcare provider suspects that you have an autoimmune disease.
Your healthcare provider may also order these tests:
DNA test of HLA-related genes. This looks at the DNA from immune system cells taken from a blood sample.
HLA antibodies. People who have been pregnant or get a blood transfusion or organ transplant may have antibodies that will react with HLA antigens on a new transplant. It's common to test people for these antibodies before the transplant to find out whether they are likely to reject the transplant.
Many things may affect your lab test results. These include the method each lab uses to do the test. Even if your test results are different from the normal value, you may not have a problem. To learn what the results mean for you, talk with your healthcare provider.
Results of HLA typing vary according to a number of factors, including your age, the type of transplant, and your underlying disease. The results will show the degree to which HLA antigens match between you and the donor.
The test requires a blood sample, which is drawn through a needle from a vein in your arm.
Taking a blood sample with a needle carries risks that include bleeding, infection, bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight stinging sensation or pain. Afterward, the site may be slightly sore.
Other factors aren't likely to affect your results.
You don't need to prepare for this test.
Bayhealth is Southern Delaware’s healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women’s services.