PHENYLPROPANOLAMINE (Prolamine®, Phenyldrine®, Dexatrim®, Acutrim®) is a decongestant. It can help relieve nasal or sinus congestion (stuffiness). Combined with a reduced calorie diet, it can help you to lose weight by decreasing your appetite. Generic phenylpropanolamine extended-release tablets and capsules are available.
NOTE: This drug is discontinued in the United States.
They need to know if you have any of the following conditions:
blood vessel disease
difficulty urinating (urinary retention)
heart disease or heart rhythm problems
high blood pressure
over active thyroid
an unusual or allergic reaction to phenylpropanolamine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take phenylpropanolamine extended-release tablets or capsules by mouth. Follow the directions on the prescription label. Swallow whole with a drink of water; do not crush or chew. Take your doses at regular intervals. Do not take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
Elderly patients over 60 years old may have a stronger reaction to this medicine and need smaller doses.
If you miss a dose, and you are taking it on a regular schedule, take it as soon as you can. If it is almost time for your next dose (less than 2 hours), take only that dose. Do not take double or extra doses.
amphetamine or other stimulant drugs
bicarbonate, citrate, or acetate products (such as sodium bicarbonate, sodium acetate, sodium citrate, sodium lactate, and potassium citrate)
medicines for colds and breathing difficulties
medicines for diabetes
medicines known as MAO inhibitors, such as phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Carbex®, Eldepryl®)
medicines for mental depression
medicines for migraine
some medicines for chest pain, heart disease, high blood pressure or heart rhythm problems
some medicines for weight loss (including some herbal products, ephedrine, dextroamphetamine)
St. John's wort
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check before starting or stopping any of your medicines.
If you are taking phenylpropanolamine for a cold, check with your prescriber or health care professional if your condition has not improved within 7 days, or if you have a high fever.
If nervousness, dizziness, sleeplessness, or palpitations occur, stop using phenylpropanolamine and consult a health care professional.
If phenylpropanolamine extended-release products make it difficult for you to sleep at night; take your last dose at least 12 hours before bedtime.
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or Uncommon:
dizziness, or fainting spells
numbness or tingling in the hands or feet
rapid or troubled breathing
severe, persistent, or worsening headache
fast or irregular heartbeat, palpitations
increased blood pressure
pain or difficulty passing urine
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
loss of appetite
nausea, stomach upset
restlessness or nervousness
Keep out of the reach of children in a container that small children cannot open.
Most products should be stored below 30 degrees C (86 degrees F). Follow manufacturer's advice on storage of specific products. Throw away any unused medicine after the expiration date.
PHENYLPROPANOLAMINE (Propagest®, Acutrim®, Dexatrim®, and others) is a decongestant. It can help relieve nasal or sinus congestion (stuffiness). Combined with a reduced calorie diet, it can help you to lose weight by decreasing your appetite. Generic phenylpropanolamine tablets and capsules are available.
Take phenylpropanolamine tablets or capsules by mouth. Follow the directions on the prescription label. Swallow with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose (less than 2 hours), take only that dose. Do not take double or extra doses.
If phenylpropanolamine (regular-release product) makes it difficult for you to sleep at night; take the last dose of the day a few hours before bedtime.